Early indications were that Guice might have suffered a strained MCL, saying after the game that he "felt fine".
Selected in the second round of this year's draft, former LSU standout Guice went down awkwardly as he was tackled from behind on an impressive 34-yard scamper negated by a holding penalty. This is a huge blow to a Washington offense that was expecting big things from Guice, the No. 59 overall pick in this year's draft. Kelley, a 2016 undrafted free agent who began last season as the starter, has gone from "Fat Rob" to "Fit Rob" and should now be considered the front-runner. Gruden has said there's competition for the No. 1 job along with Thompson, who's coming back from a broken fibula. "He's one of those guys we're expecting a lot out of him".
In camp, Guice had been splitting first-team carries with Kelley and Samaje Perine. It's not clear whether that previous injury made him more susceptible to the torn ACL, but there were National Football League teams that did extra evaluation on his medical status leading up to the draft because of that knee.
In Weeks 11-17, Perine averaged 2.65 yards after contact per attempt, ranking 12th among running backs with at least 100 attempts in said span.