"Following an attack this morning on a bus driving children in Dahyan Market, northern Saada, (an ICRC-supported) hospital has received dozens of dead and wounded", the organization said on Twitter without giving more details. "Does the world really need more innocent children's lives to stop the cruel war on children in Yemen?". "The school bus was totally burned and destroyed".
The move comes as part of a larger sweep to disarm the east of Yemen and clear the area of Al Qaeda and ISIS.
Saudi Arabia shot down the missile, with debris killing a Yemeni man and wounding 11 others, the coalition said.
On Wednesday, a Saudi-led coalition spokesman Col.
The coalition, which is backing Yemen's government in a war with the Houthis, said its actions were "legitimate".
The ballistic missile was sacked from the northern Yemeni province of Amran towards the southern Saudi city of Jizan, said a coalition statement published by the official Saudi Press Agency.
Al-Masirah, the TV station of the armed Houthi movement, said on its Twitter account that 39 people had been killed and 51 wounded.
"This is yet another example of the blatant violations of global humanitarian law that we have seen in Yemen over the past three years-from indiscriminate and disproportionate attacks on civilians, denial of access to humanitarian aid and the use of starvation as a weapon of war-it's the people of Yemen, not the warring parties, who are paying the ultimate price".
Later on Thursday, airstrikes hit the Yemeni capital, Sanaa, and sounds of the blasts reverberated across the city's southern and western neighborhoods.
Yemen's stalemated, three-year war has killed over 10,000 people, badly damaged Yemen's infrastructure and crippled its health system.
The Iran-backed Houthis have in recent months ramped up missile attacks against Saudi Arabia, which Riyadh usually says it intercepts. The coalition faces widespread global criticism for its airstrikes in Yemen that kill civilians.
Yemen has been devastated by a conflict that escalated in early 2015, when the Houthis seized control of much of the west of the country and forced President Abdrabbuh Mansour Hadi to flee overseas.
USA bombs. US targeting.
But the coalition denied carrying out any attacks in the city, saying it follows a 'strict and transparent approach based on the rules worldwide law'.
The war in the Arab world's poorest country has left almost 10,000 people dead and triggered what the United Nations describes as the world's worst humanitarian crisis.
The fight for the port of Hodeida, a key lifeline for supplies and aid for Yemen's population on the brink of starvation, has become the latest battleground in the devastating war.
The U.N. special envoy for Yemen, Martin Griffiths, has been pushing to bring the warring parties to restart peace talks.
The attack on Jazan was the second ballistic missile fired at Saudi Arabia by the Iran-backed rebels this week.