Hayek explained this in terms of simple arithmetic: "If the movie's budget is $10m, the [male] actor has to understand that if he is making $9.7 million, it is going to be hard for equality".
The Oscar-winning actress called Weinstein "her monster", after his treatment of her on the set of 2002's Frida - an accusation Weinstein denied.
The actress and producer, who says she has sold a raft of female-led projects "that I had been trying to make for 10 years" since the Weinstein scandal shook up Hollywood, said real change was happening.
Salma Hayek has spoken out against Harvey Weinstein's denials of sexual abuse against herself and actress Lupita Nyong'o, saying he hadn't responded to any other actresses' claims in the same way because they were both women of color.
"On these steps today stand 82 women representing the number of female directors who have climbed these stairs since the first edition of the Cannes Film Festival in 1946".
"The men are terrified".
"It was a strategy by the lawyers, because we are the easiest to get discredited", Hayek said. The predators are hiding. "You feel it. It's a very palpable atmosphere". Emma Stone revealed that throughout her career some men have taken pay cuts in order to increase her salary.
Which was why women had to "be impatient", she urged. He later challenged allegations by N'yongo, who said Weinstein sexually harassed her in 2011 while she was still a college student.
Speaking to reporters on Sunday, Hayek argued that Weinstein singled out Nyong'o and Hayek because they are women of color, while most of the accusers were not. It is a proven fact unfortunately.
"They're all busy. The change already happened".
"We should have come together, because that's what's made a difference".
"It is a very exciting time for men now". But she also had a warning for these women: "they still want to pay you the exploitative salary they paid you before".
"A lot of handsome peaceful men have been the victims of the bullying of men who think that the identity of a man has to do with violence", the actress added.
"This is a new era for men", Hayek said.
The interview took place the day after Hayek walked the Cannes red carpet with the likes of Wonder Woman director Patty Jenkins, A Wrinkle in Time director Ava DuVernay, and actresses Kristen Stewart, Jane Fonda, Cate Blanchett, and Marion Cotillard, as part of a group of 82 women protesting gender inequality.
Her refusals of massages, showers and sex enraged him, she wrote, adding: "I don't think he hated anything more than the word "no".