Kids, Antibiotics and Kidney Stones

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Over the past 30 years, the overall prevalence of kidney stones has risen by 70pc, particularly among young women and adolescents, despite it being previously rare in the latter.

It was found that taking antibiotics increases the likelihood of kidney stones from 2.3 times (sulphonamides) to 1.3 times (broad spectrum penicillins), depending on the type of antibiotic. In such cases, a urologist may need to remove the kidney stones or break them into smaller pieces.

USA pediatric researchers found that children and adults treated with certain antibiotics had a greater risk of developing kidney stones.


He's the first who links antibiotics to kidney stones. They include widely prescribed drugs like Bactrim, Keflex, Cipro, Augmentin, and amoxicillin. Around 30 percent of the prescribed antibiotic files are not the right medication according to Tasian.

Tasian says, there is no certified way to reduce the risk of conditions related to antibiotics intake today but there will be a solution very soon.

For Emma, drinking lots of water helps keep the kidney stones from coming back-a fear she now lives with. Cephalosporins, fluoroquinolones and nitrofurantoin were also associated with increased risk.


Now, that the link has been established between antibiotics and stones.

For their study, the investigators determined the association between 12 classes of oral antibiotics and nephrolithiasis in a population-based study within 641 general practices providing electronic health record data for more than a 13 million children and adults from 1994 to 2015 in the United Kingdom.

The data included the treatment history of 26,000 individuals with kidney stones, which the team compared with the health records of nearly 260,000 people who had not developed kidney stones (the controls).


Results Exposure to any of five different antibiotic classes 3-12 months before index date was associated with nephrolithiasis. For the broad-spectrum penicillins, the risks were increased by 27%. Kidney stones are more common in adults than in kids, but more children and teenagers are getting them lately and some doctors at the Children's Hospital of Philadelphia think antibiotics may play a role.

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