However, City are now 16 points clear of second-placed United, meaning a defeat for Jose Mourinho's men at Old Trafford against a West Brom side on the brink of relegation - kick-off is at 1500 GMT (11pm Malaysia) - would wrap up a third title in seven seasons.
If City fans had to pick who they'd like winning the title against, it would have definitely been cross-town rivals Manchester United last weekend - but to win thanks to United falling to defeat at home to the Premier League's worst club will put a wry smile on a number of faces in the city.
Guardiola failed to win a trophy during his first season in English football but has now added the Premier League to the EFL Cup crown collected against Arsenal in February.
Manchester City would be crowned champions if the Red Devils is defeated in the game. The club are now rockbottom of the league standings with 21 points, and they face a near improbable task of beating the drop with a 10-point deficit and just five games remaining in the season.
Guardiola might not have seen Jay Rodriguez's 73rd-minute winning goal at Old Trafford because he was playing golf with his son instead of watching the match.
The setup provided Pogba more creative freedom and showed the damage he could do with such license in the derby win.
Because of goal difference, United realistically needed to win all of their six remaining games and hope City lost their last five matches.
"They won the title because they were the best team, because they won a great amount of points".
Former England worldwide Gary Lineker, who now work as a television presenter, tweeted: "Congratulations to @ManCity on winning the Premier League title". "The important thing is to have the chance to win at home". I'm a very family-orientated person anyway.
The 47-year-old also took the German title three times with Bayern Munich, but he believes the unique strength in depth and physical demands of the Premier League makes this triumph among his very best. "They don't understand anything", he said. The skipper has missed the previous three league games for the bottom side. Both full-backs will need to be more proactive in their attacking play down the wings. "It's incredible. They have been unbelievable".