The Bhoys have in contrast struggled in Europe, but would take qualifying for the Europa League as a positive sign. We've recovered well over the weekend and we've prepared properly so we're ready to go.
The 29-year-old said: "It will be very hard".
Confirmed: Celtic lineup v Anderlecht at Celtic Park
"There will be noise as soon as we come on the pitch".
Brendan Rodgers' switch to three at the back at half-time allowed Celtic to flow with much more objective in attack through Kieran Tierney down the left flank.
Dembele who scored 32 goals across all competitions last term missed the first two months of the season with a hamstring injury.
"If we can survive and stay level, then maybe we have a chance to do something".
"For Celtic winning 3-0 away from home in European football has been a tough ask, certainly in previous years, so to go and get that gives us great confidence going into tomorrow night that we can get a result", he told a press conference.
"You can say we're going to try to score in the first five minutes - and then you lose a goal in the first five minutes and it will be doubly hard".
The final stages were more about not conceding and there were sighs of relief among the green and white when Gordon parried a 25-yard drive from Anderlecht captain Sofiane Hanni, and with the Belgian side failing to find a second goal, the final minutes were less nervy.
Vanhaezebrouck knows that if his charges are to pull of an upset and qualify, they will need everything to be in their favour against Celtic.
"But to overcome the three-goal difference to continue, everything has to be ideal and we also need all the luck in the world. There is always a small chance". But that's not our main goal. We have to be realistic.