The Missouri signal-caller, hoping to find a teammate across the middle, accidentally connected with Idaho defensive back Armond Hawkins for an interception on the opening play of the game.
Albert Okwuegbunam had three touchdown receptions while Emanuel Hall and Richaud Floyd also had touchdown grabs.
Missouri's quick-tempo offense was fully on display, as the Tigers produced six scoring drives that lasted less than 1:35 in length. The 10-yard strike was a pass from Mason Petrino, the first touchdown of Petrinos career. Big plays helped the Tigers (2-5) answer the score and a punt return touchdown put Missouri on top for good. Alfonso Onunwor led the Vandals with eight catches for 89 yards.
Drew Lock threw for 467 yards and six TDs as the host Tigers (2-5) blasted the Vandals (2-5). The Tigers led 51-14 at halftime.
"I was a little bit surprised, but at the same time I've been in these situations before, and I was just ready to step up when the team needed me", Bartolotta said.
"I just realized how I could utilize my talent", Hall said. Odom said Crockett was limited in Tuesday's practice, and his status against Idaho is questionable.
"We definitely game-planned that", Okwuegbunam said.
Idaho's starting center Connor Vrba was injured and did not play.
"We did some good things that we're continuing to build on", Odom said of his defense. Four plays later, the Tigers turned the turnover into points as Okwuegbunam caught his third touchdown pass of the day making it 34-7 Mizzou with 2:01 left in the first quarter.
"We've just got to keep fighting", Petrino said. Zion Dixon moved over from guard to replace him, and freshman Maxim Moore got his first start at guard. "I thought they got beat a few times, but they were competing". Last week against Georgia, he had 141 yards and two touchdowns.
RUSHING-Idaho, Duckworth 13-74, Saunders 9-13, Petrino 3-0, Thigpen 3-(minus 2), Ma.Linehan 10-(minus 4).
Redshirt junior kicker Nick Bartolotta made his first career start at Missouri on Saturday after junior Tucker McCann was suspended for a violation of team policies.
Freshman Larry Rountree led the Tigers with 12 carries for 97 yards, and Ish Witter added nine rushes for 41 yards and two touchdowns.
With the win, Mizzou improves to 2-5 (0-4 SEC).